$3.73-0.07 (-1.84%)
Fulcrum Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops small molecules to improve the lives of patients with genetically defined diseases in the areas of high unmet medical need in the United States.
Fulcrum Therapeutics, Inc. in the Healthcare sector is trading at $3.73 with a market capitalization of $239M. Wall Street consensus targets $5.43 (7 analysts), implying a +45.5% move over the next 12 months. The stock is currently near its 52-week low of $2.83, remaining 56.1% below its 200-day moving average. On fundamentals, Piotroski 4/9 shows mixed financial quality, Altman Z in the safe zone. The Whystock Score of 80/100 reflects bullish alignment across trend, valuation and analyst targets.
| Metric (USD) | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 |
|---|---|---|---|---|---|
| Total Revenue | $0 | $0 | $0 | $0 | $0 |
| Gross Profit | β | β | β | β | β |
| Operating Income | -$22.19Mβ | -$22.69Mβ | -$21.86Mβ | -$19.82Mβ | -$20.40M |
| Net Income | -$18.89Mβ | -$20.33Mβ | -$19.59Mβ | -$17.30Mβ | -$17.66M |
Fulcrum Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops small molecules to improve the lives of patients with genetically defined diseases in the areas of high unmet medical need in the United States. Its clinical-stage produ...
For Fulcrum Therapeutics, the modeled fair value has been reset from about US$19.00 to roughly US$5.43, a cut of around 71% that pulls implied price targets sharply lower. Much of this reset aligns with recent analyst commentary that focuses on the discontinuation of pociredir, class wide PRC2 safety concerns, and a shift to viewing the stock mainly through its cash position and review of strategic alternatives. As you read on, you will see how this evolving narrative is shaping expectations...
Why Fulcrum Therapeutics Stock Is Back in Focus Fulcrum Therapeutics (FULC) is back on investors' radar after the company scrapped development of its lead sickle cell disease drug, pociredir, and moved quickly into a deep restructuring and review of options. See our latest analysis for Fulcrum Therapeutics. The discontinuation of pociredir and the sweeping restructuring have driven sharp volatility. The stock is down about 52% on a 1 year total shareholder return basis. The 3 year total...
The heavy selling pressure might have exhausted for Fulcrum Therapeutics (FULC) as it is technically in oversold territory now. In addition to this technical measure, strong agreement among Wall Street analysts in revising earnings estimates higher indicates that the stock is ripe for a trend reversal.
Fulcrum Therapeutics stock sinks 51% after ending pociredir development in SCD due to FDA cancer-risk concerns, leaving no clinical-stage assets.
The selloff highlighted the risks facing smaller companies operating in biotechnology and emerging technology.